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Nyack College Arts and Sciences News

Dr. Yan researches diabetes and Metformin effects

Posted by Fernando.Arzola on Monday October 21, 2013

Dr. Wenbo Yan, Assistant Professor of Biology, publishes in Carcionogenesis: Integrative Cancer Research. Carcionogenesis is a multi-disciplinary journal that brings together all the varied aspects of research that will ultimately lead to the prevention of cancer in man. 

The article, “Metformin Targets c-MYC Oncogene to Prevent Prostate Cancer, investigates the effect of metformin on c-myc expression and prostate cancer progression. Metformin, an old anti-diabetes drug, may inhibit prostate intraepithelial neoplasia transforming to cancer lesion via reducing c-MYC, an “old” over-expressed oncogene. This study explores chemopreventive efficacy of metformin in prostate cancer and its link to cMYC in-vitro and invivo.

For more information:

http://carcin.oxfordjournals.org/content/early/2013/10/11/carcin.bgt307.abstract

Dr. Yan also presents paper at the 2013 Annual Meeting of the American Society for Bone and Mineral Research. ASBMR is a professional, scientific and medical society established to bring together clinical and experimental scientists involved in the study of bone and mineral metabolism.

The paper is entitled, "Metformin stimulates compact bone mesenchymal stem cells and accelerates wound healing in a Type 2 Diabetes mouse model."

For more information: http://www.asbmr.org/ASBMR-abstracts

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